Childhood-onset hypophosphatasia is a rare, mildform of hypophosphatasia characterized by onset after six months of age and widely variable clinical features from low bone mineral density for age, to unexplained fractures,skeletal deformities,and rickets with short stature and waddling gait. The disease is childhood hypophosphatasia (MONDO_1010168, a Monarch Disease Ontology entry). Also known as: hypophosphatasia of childhood, pediatric hypophosphatasia.