A neurodevelopmental disorder caused by variation in the CAMK2D gene. This disorder is characterised by intellectual disability, speech and motor delay, behavioural problems and dilated cardiomyopathy. Patients often present brain structural anomalies and hypotonia, and less frequently, seizures. The disease is CAMK2D-related neurodevelopmental disorder and dilated cardiomyopathy (MONDO_1040008).