Birt-Hogg-Dubé syndrome (Orphanet rare-disease nomenclature id Orphanet_122) can be described as follows. Birt-Hogg-Dube (BHD) syndrome is characterized by skin lesions, kidney tumors, and pulmonary cysts that may be associated with pneumothorax. It is a rare clinicopathologic condition named after the three Canadian physicians who reported the syndrome in 1977. Also known as: Birt-Hogg-Dube syndrome, fibrofolliculomas with trichodiscomas and acrochordons.