Congenital neuronal ceroid lipofuscinosis (CNCL) is a severe form of neuronal ceroid lipofuscinosis (NCL; see this term) with onset at birth characterized by primary microcephaly, neonatal epilepsy, and death in early infancy. The disease is Congenital neuronal ceroid lipofuscinosis (Orphanet rare-disease nomenclature term Orphanet_168486). Also known as: Congenital NCL.