The newly described 22q11.2 microduplication syndrome (dup22q11 syndrome) is the association of a broad clinical spectrum and a duplication of the region that is deleted in patients with DiGeorge or velocardiofacial syndrome (DG/VCFS; see this term), establishing a complementary duplication syndrome. The disease is Orphanet_1727 (22q11.2 microduplication syndrome). Also known as: Dup(22)(q11), Duplication 22q11.2, Trisomy 22q11.2.