Orphanet rare-disease nomenclature term Orphanet_217330 (Hyperuricemia - anemia - renal failure) can be described as follows. Familial juvenile hyperuricemic nephropathy type 2 is a rare autosomal dominantly inherited disease of childhood characterized by hypoproliferative anemia, hyperuricemia and slowly progressing kidney failure due to dysregulation of the renin-angiotensin system (RAS). Also known as: FJHN type 2, Familial juvenile hyperuricemic nephropathy type 2, REN-associated FJHN, REN-associated familial juvenile hyperuricemic nephropathy, REN-associated kidney disease.