Muscular pseudohypertropy - hypothyroidism, also known as Kocher-Debre-Semelaigne syndrome is a rare disorder characterized by pseudohypertrophy of muscles due to longstanding hypothyroidism (see this term). The disease is Orphanet_2349 (Muscular pseudohypertrophy - hypothyroidism). Also known as: Hoffman syndrome, Kocher-Debré-Semelaigne syndrome.