Microcephaly - cardiac defect - lung malsegmentation syndrome is a very rare syndrome characterized by the combination of microcephaly, heart defects, renal hypoplasia, lung segmentation defects and cleft palate. The disease is Microcephaly - cardiac defect - lung malsegmentation (Orphanet_2516, an Orphanet rare-disease nomenclature term). Also known as: Ellis-Yale-Winter syndrome.