Epidermolysis bullosa simplex with muscular dystrophy (Orphanet rare-disease nomenclature entry Orphanet_257) (EBS-MD) is a basal subtype of epidermolysis bullosa simplex (EBS, see this term) characterized by generalized blistering associated with muscular dystrophy. Also known as: EBS-MD, Limb-girdle muscular dystrophy with epidermolysis bullosa simplex.