Autosomal dominant limb-girdle muscular dystrophy type 1B (Orphanet_264) (LGMD1B) is a limb girdle muscular dystrophy (LMGD; see this term)a laminopathy, characterized by progressive limb girdle weakness, usually affecting the pelvic girdle before humeral muscles, mild jointoint contractures, age-related atrioventricular cardiac conduction disturbances and dilated cardiomyopathyinvolvement is frequently associated. Also known as: LGMD1B, Limb-girdle muscular dystrophy due to lamin A/C deficiency.