Young-onset Parkinson disease (YOPD) is a form of Parkinson disease (PD), characterized by an age of onset between 21-45 years, rigidity, painful cramps followed by tremor, bradykinesia, dystonia, gait complaints and falls, and other non-motor symptoms. A slow disease progression and a more pronounced response to dopaminergic therapy are also observed in most YOPD forms. The disease is Orphanet_2828 (Young adult-onset Parkinsonism). Also known as: Early-onset Parkinson disease, Young-onset Parkinson disease.