Tyrosinemia type 2 is an inborn error of tyrosine metabolism characterized by hypertyrosinemia with oculocutaneous manifestations and, in some cases, intellectual deficit. The disease is Orphanet rare-disease nomenclature identifier Orphanet_28378 (Tyrosinemia type 2). Also known as: Keratosis palmoplantaris - corneal dystrophy, Oculocutaneous tyrosinemia, Richner-Hanhart syndrome, Tyrosinemia due to TAT deficiency, Tyrosinemia due to tyrosine aminotransferase deficiency, Tyrosinemia type II.