8q21.11 microdeletion syndrome (Orphanet_284160, an Orphanet rare-disease nomenclature id) encompasses heterozygous overlapping microdeletions on chromosome 8q21.11 resulting in intellectual disability, facial dysmorphism comprising a round face, ptosis, short philtrum, Cupid's bow and prominent low-set ears, nasal speech and mild finger and toe anomalies. Also known as: Del(8)(q21.11), Deletion 8q21.11, Monosomy 8q21.11.