Alopecia-intellectual disability syndrome (Orphanet rare-disease nomenclature identifier Orphanet_2850) can be described as follows. Alopecia-intellectual deficit syndrome is an extremely rare syndrome described in less than 20 families to date and characterized by total or partial alopecia associated with intellectual deficit. The syndrome can be associated with other anomalies such as seizures, sensorineural hearing loss, delayed psychomotor development, and/or hypertonia. Also known as: Perniola-Krajewska-Carnevale syndrome.