Isolated polycystic liver disease (PCLD) is a genetic disorder characterized by the appearance of numerous cysts spread throughout the liver and that in most cases is described as autosomal dominant polycystic liver disease (ADPCLD). The disease is Isolated polycystic liver disease (Orphanet_2924, an Orphanet rare-disease nomenclature term). Also known as: ADPCLD, Autosomal dominant polycystic liver disease, PCLD.