Acro-oto-ocular syndrome is a very rare disorder associating pseudopapilledema (optic disc swelling not secondary to increased intracranial pressure), mixed hearing loss, facial dysmorphism and limb extremity anomalies. The disease is Orphanet rare-disease nomenclature identifier Orphanet_2980 (Acro-oto-ocular syndrome). Also known as: Pseudopapilledema - blepharophimosis - hand anomalies.