Hereditary central diabetes insipidus is a rare genetic subtype of central diabetes insipidus (CDI, see this term) characterized by polyuria and polydipsia due to a deficiency in vasopressin (AVP) synthesis. The disease is Hereditary central diabetes insipidus (Orphanet rare-disease nomenclature term Orphanet_30925). Also known as: Hereditary CDI, Hereditary neurogenic diabetes insipidus.