Orphanet rare-disease nomenclature entry Orphanet_3253 (Zlotogora-Ogur syndrome) is an ectodermal dysplasia syndrome characterized by hair, skin and teeth anomalies, facial dysmophism with cleft lip and palate, cutaneous syndactyly and, in some cases, intellectual disability. Also known as: CLPED1, Cleft lip/palate-ectodermal dysplasia syndrome, Cleft lip/palate-syndactyly-pili torti, Syndactyly-ectodermal dysplasia-cleft/lip palate, Zlotogora-Zilberman-Tenenbaum syndrome.