Tumor necrosis factor receptor 1 associated periodic syndrome (TRAPS) is a periodic fever syndrome, characterized by recurrent fever, arthralgia, myalgia and tender skin lesions lasting for 1 to 3 weeks, associated with skin, joint, ocular and serosal inflammation and complicated by secondary amyloidosis (see this term). The disease is Orphanet rare-disease nomenclature term Orphanet_32960 (Tumor necrosis factor receptor 1 associated periodic syndrome). Also known as: Familial Hibernian fever, TNF receptor 1 associated periodic syndrome, TRAPS syndrome.