Orphanet rare-disease nomenclature identifier Orphanet_70470 (Hyperlipoproteinemia type 5) can be described as follows. A severe type of hyperlipidemia, sometimes familial, that is characterized by the elevation of both plasma CHYLOMICRONS and TRIGLYCERIDES contained in VERY-LOW-DENSITY LIPOPROTEINS. Type V hyperlipoproteinemia is often associated with DIABETES MELLITUS and is not caused by reduced LIPOPROTEIN LIPASE activity as in HYPERLIPOPROTEINEMIA TYPE I . Also known as: Fredrickson type V lipaemia, Hyperlipoproteinemia Type V, Major hyperlipidemia, familial hyperlipoproteinemia type V, familial type 5 hyperlipoproteinemia (disorder), hyperlipoproteinemia type V.