Gaucher disease type 2 (Orphanet rare-disease nomenclature identifier Orphanet_77260) is the acute neurological form of Gaucher disease (GD; see this term). It is characterized by early-onset and severe neurological involvement of the brainstem, associated with an organomegaly and generally leading to death before the age of 2. Also known as: Acute neuronopathic Gaucher disease, Infantile cerebral Gaucher disease.