Fish eye disease (FED) is a form of genetic LCAT (lecithin-cholesterol acyltransferase) deficiency (see this term) characterized clinically by corneal opacifications, and biochemically by significantly reduced HDL cholesterol and partial LCAT enzyme deficiency. The disease is Orphanet rare-disease nomenclature identifier Orphanet_79292 (Fish-eye disease). Also known as: FED, Partial LCAT deficiency.