Alpha-thalassemia is an inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture depending on the number of affected alleles. The disease is Alpha-thalassemia (Orphanet_846, an Orphanet rare-disease nomenclature term). Also known as: Alpha thalassaemia, alpha thalassemia, alpha-Thalassemia, α-thalassemia.