Diaphyseal medullary stenosis with malignant fibrous histiocytoma is a very rare autosomal dominant bone dysplasia/cancer syndrome characterized clinically by bone infarctions, cortical growth abnormalities, pathological fractures, and development of bone sarcoma (malignant fibrous histiocytoma). The disease is Diaphyseal medullary stenosis - bone malignancy (Orphanet_85182, an Orphanet rare-disease nomenclature id). Also known as: DMS-MFH, Hardcastle syndrome, Hardcastle's syndrome, bone dysplasia-medullary fibrosarcoma syndrome, diaphyseal medullary stenosis-bone malignancy syndrome, diaphyseal medullary stenosis-malignant fibrous histiocytoma syndrome.