Non-hereditary late-onset primary lymphedema, also known as Meige-like disease, is a very rare form of primary lymphedema characterized by lower limb lymphedema mostly during puberty, but a negative family history for Meige disease (see this term). The disease is Non-hereditary late-onset primary lymphedema (Orphanet_90185, an Orphanet rare-disease nomenclature identifier). Also known as: Meige-like disease.