Ataxia with vitamin E deficiency (AVED) is a neurodegenerative disease belonging to the inherited cerebellar ataxias. It is mainly characterized by progressive spino-cerebellar ataxia, loss of proprioception, areflexia, and is associated with a marked deficiency in vitamin E. The disease is Ataxia with vitamin E deficiency (Orphanet_96). Also known as: AVED, Ataxia with isolated vitamin E deficiency, Familial isolated vitamin E deficiency, Friedreich-like ataxia, Isolated vitamin E deficiency.