Fuchs endothelial corneal dystrophy (FECD) is the most frequent form of posterior corneal dystrophy (see this term) and is characterized by excrescences on a thickened Descemet membrane (corneal guttae), generalized corneal edema, with gradually decreased visual acuity. The disease is Orphanet rare-disease nomenclature entry Orphanet_98974 (Fuchs endothelial corneal dystrophy). Also known as: Endoepithelial corneal dystrophy, FECD, Late hereditary endothelial dystrophy.