The function of TBXA2R (thromboxane A2 receptor, ENSG00000006638) is as follows. Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. . [Isoform 1]: Activates adenylyl cyclase. . [Isoform 2]: Inhibits adenylyl cyclase. .