The function of Ensembl gene identifier ENSG00000012963 (UBR7, ubiquitin protein ligase E3 component n-recognin 7) is as follows. E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. .