The function of CELF2 (CUGBP Elav-like family member 2, ENSG00000048740) is as follows. RNA-binding protein implicated in the regulation of several post-transcriptional events (PubMed:11577082, PubMed:11158314, PubMed:11931771, PubMed:12649496, PubMed:14973222, PubMed:15657417). Involved in pre-mRNA alternative splicing, mRNA translation and stability (PubMed:11158314, PubMed:11931771, PubMed:12649496, PubMed:14973222, PubMed:15657417, PubMed:15894795). Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue- specific and developmentally regulated alternative splicing (PubMed:11158314, PubMed:11931771, PubMed:12649496). Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle (PubMed:11158314, PubMed:11931771). Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB (PubMed:11931771). Acts both as an activator and as a repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs (PubMed:12649496). Promotes inclusion of exon 21 and exclusion of exon 5 of the NMDA receptor R1 pre-mRNA (By similarity). Involved in the apoB RNA editing activity (PubMed:11577082). Increases COX2 mRNA stability and inhibits COX2 mRNA translation in epithelial cells after radiation injury (By similarity). Binds to the muscle-specific splicing enhancer (MSE) intronic sites flanking the TNNT2 alternative exon 5 (PubMed:11158314). Binds preferentially to UG-rich sequences, in particular UG repeat and UGUU motifs (PubMed:11931771, PubMed:15657417). Binds to apoB mRNA, specifically to AU-rich sequences located immediately upstream of the edited cytidine (PubMed:11577082). Binds AU-rich sequences in the 3'-UTR of COX2 mRNA (By similarity). Binds to an intronic RNA element responsible for the silencing of exon 21 splicing (By similarity). Binds to (CUG)n repeats (PubMed:11158314). May be a specific regulator of miRNA biogenesis (PubMed:28431233). Binds to primary microRNA pri-MIR140 and, with CELF1, negatively regulates the processing to mature miRNA (PubMed:28431233). {ECO:0000250|UniProtKB:Q9Z0H4, ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:11577082, ECO:0000269|PubMed:11931771, ECO:0000269|PubMed:12649496, ECO:0000269|PubMed:14973222, ECO:0000269|PubMed:15657417, ECO:0000269|PubMed:15894795, ECO:0000269|PubMed:28431233}.