The function of Ensembl gene identifier ENSG00000065665 (SEC61A2, SEC61 translocon subunit alpha 2) is as follows. Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. .