RNA-binding protein involved in pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12- type introns in pre-mRNAs (Probable). {ECO:0000269|PubMed:25296192, ECO:0000305|PubMed:33509932}. This is the function of GPKOW (G-patch domain and KOW motifs, Ensembl gene identifier ENSG00000068394).