The function of Ensembl gene identifier ENSG00000068784 (SRBD1, S1 RNA binding domain 1) is as follows. DNA- and histone-binding protein that localizes to the central axes of mitotic chromosomes (PubMed:39955279, PubMed:40106440). Promotes chromosome segregation by facilitating TOP2A recruitment to mitotic chromosomes, thereby preventing anaphase failure (PubMed:39955279). During prophase, safeguards the decatenation process to avoid the formation of difficult-to-resolve DNA structures, preventing chromosome missegregation (PubMed:40106440). Also contributes to the regulation of nucleus pulposus cell senescence (PubMed:38169523). {ECO:0000269|PubMed:38169523, ECO:0000269|PubMed:39955279, ECO:0000269|PubMed:40106440}.