The function of TRPC5 (transient receptor potential cation channel subfamily C member 5, Ensembl gene identifier ENSG00000072315) is as follows. Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:16284075, PubMed:38959890, PubMed:37137991). Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1 (By similarity). Acts on distinct neuronal populations in the hypothalamus to regulate innate behaviors including feeding, anxiety (flight/fight/fear), socialization, and maternal care (By similarity). {ECO:0000250|UniProtKB:Q9QX29, ECO:0000269|PubMed:16284075, ECO:0000269|PubMed:37137991, ECO:0000269|PubMed:38959890}.