The function of Ensembl gene identifier ENSG00000085511 (MAP3K4, mitogen-activated protein kinase kinase kinase 4) is as follows. Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. .