The function of Ensembl gene identifier ENSG00000085514 (PILRA, paired immunoglobin like type 2 receptor alpha) is as follows. Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP. . (Microbial infection) Acts as an entry co-receptor for herpes simplex virus 1. .