Inhibits the activity of the vacuolar-type ATPase (V-ATPase) by inducing disassembly of the V-ATPase complex (PubMed:38593795). Protects neuronal cells against oxidative stress (By similarity). Required for kidney bicarbonate secretion (By similarity). . This is the function of TLDC2 (TBC/LysM-associated domain containing 2, Ensembl gene identifier ENSG00000101342).