The function of ENSG00000102195 (GPR50, G protein-coupled receptor 50) is as follows. G protein-coupled receptor that plays a role in numerous physiological processes including regulation of energy metabolism, neurite outgrowth or cell migration (PubMed:19699797). Promotes self- renewal and neuronal differentiation of neural progenitor cells through activation of the NOTCH and WNT/beta-catenin signaling pathways (By similarity). Modulates the KAT5-dependent glucocorticoid receptor signaling by modulating KAT5 subcellular compartmentalization (PubMed:21858214). Also plays a role in the activation TGFBR1 in the absence of TGFBR2 by interfering with FKBP1A binding to TGFBR1, leading to induction of both canonical and non-canonical SMAD signaling pathways resulting in inhibition of proliferation or promotion of migration (PubMed:29572483). {ECO:0000250|UniProtKB:O88495, ECO:0000269|PubMed:16778767, ECO:0000269|PubMed:19699797, ECO:0000269|PubMed:21858214, ECO:0000269|PubMed:29572483}. [C-terminal domain]: Upon cleavage by CAPN1, functions as a scaffold in the nucleus for interacting partners such as GTF2I to promote FOS promoter activation. {ECO:0000250|UniProtKB:O88495, ECO:0000269|PubMed:19699797, ECO:0000269|PubMed:21858214, ECO:0000269|PubMed:31900622}.