The function of Ensembl gene identifier ENSG00000103154 (NECAB2, N-terminal EF-hand calcium binding protein 2) is as follows. May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation. .