The function of PPP6R1 (protein phosphatase 6 regulatory subunit 1, Ensembl gene identifier ENSG00000105063) is as follows. Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF. .