The function of ENSG00000106392 (C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1) is as follows. Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins (PubMed:11677243). Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development (By similarity). {ECO:0000250|UniProtKB:Q7K237, ECO:0000250|UniProtKB:Q9JJ06, ECO:0000269|PubMed:11677243}.