Clinical precedence for drugs with investigational or approved indications targeting according to their curated mechanism of action. Source: ChEMBL.
Drug information | Disease information | Clinical trials information | |||||
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Drug | Type | Mechanism Of Action | Action Type | Disease | Phase | Status | Source |
RNA and protein baseline expression for . Source: ExpressionAtlas, HPA and GTEx.
Gene Essentiality assessment for obtained through CRISPR loss-of-function screens in a wide range of cancer cell lines. Source: DepMap Portal.
Physical and functional molecular interactions with . Source: Open Targets, IntAct, Signor, Reactome, String
Phenotypes associated with murine homologue(s). Source: MGI.
Mouse gene | Phenotype | Category | Allelic composition |
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