The function of HDDC2 (HD domain containing 2, Ensembl gene identifier ENSG00000111906) is as follows. Catalyzes the dephosphorylation of the nucleoside 5'- monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP). .