Adapter protein that plays a role downstream of GNA15 to stimulate Ras activation and subsequent phosphorylation of ERK1/2 independently of phospholipase Cbeta signaling (PubMed:12748287, PubMed:21486497). Mechanistically, interacts with GNA15 and SOS2 to form a macromolecular signaling complex which has a high affinity for HRAS (PubMed:20639119). Additionally, participates in signaling via other G-alpha proteins like GNA14, activating NF-kappa-B through Ras and ERK pathways (PubMed:22711498). Beyond signaling, supports protein homeostasis by cooperating with HSP40 in the HSP70 chaperone cycle, promoting protein folding through the regulated dissociation of the HSP70 inhibitor HSPBP1 (PubMed:14503850). {ECO:0000269|PubMed:12748287, ECO:0000269|PubMed:14503850, ECO:0000269|PubMed:20639119, ECO:0000269|PubMed:21486497, ECO:0000269|PubMed:22711498}. This is the function of Ensembl gene identifier ENSG00000113312 (TTC1, tetratricopeptide repeat domain 1).