The function of Ensembl gene identifier ENSG00000115718 (PROC, protein C, inactivator of coagulation factors Va and VIIIa) is as follows. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PubMed:25618265, PubMed:39880037). Exerts a protective effect on the endothelial cell barrier function (PubMed:25651845). {ECO:0000269|PubMed:25618265, ECO:0000269|PubMed:25651845, ECO:0000269|PubMed:39880037}.