The function of TRIM62 (tripartite motif containing 62, ENSG00000116525) is as follows. E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C- type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways (PubMed:26488816). E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2 (PubMed:23402750). {ECO:0000269|PubMed:23402750, ECO:0000269|PubMed:26488816}.