The function of Ensembl gene identifier ENSG00000118523 (CCN2, cellular communication network factor 2) is as follows. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis (PubMed:39414788). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor- induced DNA synthesis. {ECO:0000269|PubMed:10614647, ECO:0000269|PubMed:12553878, ECO:0000269|PubMed:39414788}.