Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. This is the function of TAS2R8 (taste 2 receptor member 8, Ensembl gene identifier ENSG00000121314).