The function of GHSR (growth hormone secretagogue receptor, ENSG00000121853) is as follows. G protein-coupled receptor specific to ghrelin, an appetite- regulating peptide hormone commonly found in stomach (PubMed:35027551, PubMed:39833471). Upon activation, stimulates appetite and promotes growth hormone secretion (PubMed:11322507, PubMed:10604470, PubMed:35027551, PubMed:39833471). Also binds other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692, 429, MK- 0677, adenosine) (PubMed:11322507, PubMed:10604470). {ECO:0000269|PubMed:10604470, ECO:0000269|PubMed:11322507, ECO:0000269|PubMed:35027551, ECO:0000269|PubMed:39833471}.