The function of Ensembl gene identifier ENSG00000122679 (RAMP3, receptor activity modifying protein 3) is as follows. Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene- related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G protein-coupled estrogen receptor 1 (GPER1) (PubMed:23674134, PubMed:9620797). Required for the transport of CALCRL and GPER1 receptors to the plasma membrane (PubMed:23674134, PubMed:9620797). Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner (PubMed:23674134). Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2 (PubMed:32296767). Together with CALCR, act as a receptor complex for amylin/IAPP (PubMed:35324283). {ECO:0000269|PubMed:23674134, ECO:0000269|PubMed:32296767, ECO:0000269|PubMed:35324283, ECO:0000269|PubMed:9620797}.